![]() ![]() Predictors of recovery following allogeneic CD34+-selected cell infusion without conditioning to correct poor graft function. In press.Ĭuadrado MM, Szydlo RM, Watts M, Patel N, Renshaw H, Dorman J, Lowdell M, Ings S, Anthias C, MadrigalA, Mackinnon S, Kottaridis P, Carpenter B, HoughR, Morris E, Thomson K, Peggs KS, Chakraverty R. Off-the-shelf EBV-specific T Cell Immunotherapy for EBV-associated PTLD. CMV cell-mediated immunity and CMV infection after allogeneic hematopoietic cell transplantation: the REACT study. In press.Ĭhemaly RF, El Haddad L, Winston DJ, Rowley SD, Mulane KM, Chandrasekar P, Avery RK, Hari P, Peggs KS, Kumar D, Nath R, Ljungman P, Mossad SB, Dadwal SS, Blanchard T, Shah DP, Jiang Y, Ariza-Heredia E. Tumor control by novel CD25-targeting antibodies preserving IL-2 signaling on effector T cells. ![]() Solomon I, Amann M, Goubier A, Vargas F, Zervas D, Qing C, Henry J, ?ledzi?ska A, Werner Sunderland M, Demane D, Clancy J, Georgiou A, Salimu J, Merchiers P, Brown M, Flury R, Eckmann J, Murga C, Sam J, Sutmuller R, Peggs KS, Quezada S. More recently he has established the clinical translational side of the academic CAR-T cell programme at UCLH. His research interests include viral infections, adoptive cellular therapies, and regulatory checkpoint-directed immune-therapeutics. He runs a joint research laboratory with Professor Sergio Quezada in the UCL Cancer Institute and is co-founder of the UCL spinout company Achilles Therapeutics. After taking the position head of adult stem cell transplantation services at UCLH, he spent three years at MSKCC in the laboratory of Dr James Allison, contributing to the body of work underpinning checkpoint blockade that led to the Nobel Prize for Medicine in 2018. Following specialisation in haematology, he spent three years developing cellular therapies for viruses at UCL. Karl completed his medical training at Cambridge and Oxford Universities. Karl Peggs is a professor of transplant science and cancer immunotherapy, scientific director NIHR blood and transplant research unit for stem cells and immunotherapies, and clinical and scientific director of the Sir Naim Dangoor Centre for Cellular Therapy, UCLH. ![]()
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